Is there a theory which explains the values of all fundamental physical constants? Is there a theory which explains why the gauge groups of the standard model are as they are, why observed space-time has 3 + 1 dimensions, and why all laws of physics are as they are? Do "fundamental physical constants" vary over time? Are any of the particles in the standard model of particle physics actually composite particles too tightly bound to observe as such at current experimental energies? Are there fundamental particles that have not yet been observed and if so which ones are they and what are their properties? Are there unobserved fundamental forces implied by a theory that explains other unsolved problems in physics?